DIRMC

A Database of Immunotherapy-Related Molecular Characteristics

Analysis Interface

In the analysis interface, you can clearly see the specific target of each type of immunotherapy. The target with a red background indicates that the target has an approved immunotherapy, and the yellow background indicates that the drug for the target is currently in the clinical research stage. If you want to know the current research status of a specific target, which drugs are approved, and what diseases are these drugs designed for, you can learn more by clicking on the specific target.

If you want to predict the binding affinity of both MHC (including, MHC I and MHC II) and peptide, and TCR and peptide, you can choose different methods to predict the relevant results by selecting the option of MHC & peptide or TCR & peptide in the "Predict you want" box below.
Predict you want
CD80/86
ICOSL
OX40L
CD70
CD40
GITRL
41BBL
HHLA2
LIGHT
MHC I/II-antigen
CD80/86
PD-L1/PD-L2
HVEM
B7-H3/B7-H4
HLA-E
Galectin-9/PtdSer/HMGB1/CEACAM1
PVR/Nectin-2/Nectin-3
CD47
PSGL-1
Nectin-2
CD48
CD200
PVR/Nectin-1
A2aR
CD28
ICOS
OX40
CD27
CD40L
GITR
41BB
CD28H
HVEM
TCR
LAG-3
KIR
CTLA-4
PD-1
BTLA/CD160
?
NKG2A/CD94
TIM-3
TIGIT
SIRPα
VISTA
PVRIG
2B4
CD200R
CD96
A2aR
Network Analysis Results
Gene
Target
Drug
Disease
Analysis Result Table
CSV
Network Analysis Results
This target has not yet been studied in clinical trials, and there is no clear evidence of target interaction. We will update the information in time if relevant data appears in the follow-up. If you have evidence to support this target relationship, you can also provide it to us on the Submission page, and we greatly appreciate your submission.
CopyRight © Center for Bioinformatics, Harbin Institute of Technology, China.